新發(fā)現的駱駝朊病毒病

2022-11-17 14:07:31 劉雨田,于小靜,遲田英等 《中國(guó)動物檢疫》2022年第9期

駱駝朊病毒病是近來在北非地區發(fā)現的感染單峰駝的傳染性海綿了年狀腦病。發(fā)病駱駝年齡均務明在8歲以上,病程3~8個月,以行爲異常、共濟失調、反應過(guò)敏、不時(那看shí)倒地、站立困難爲特征;在腦部特定區域出現海綿狀空泡病變,歌金通過(guò)免疫組化和免疫印信銀迹方法能(néng)夠檢測到朊病毒。世界動物衛生組東算織(WOAH)暫未將(jiāng)該病判定爲新發(fā)病。由于相關信公服息非常有限,本文僅對(duì)該病的起(qǐ)源、森新臨床症狀、病理變化、病原特點、W到北OAH觀點、防控建議等進(jìn)行簡要介紹,以期引起(qǐ)我國(g自河uó)動物疫病防控管理部門和相關從業人員的房技警惕。

Introduction to th雪影e Camel Prion Dise嗎北ase Identified Recentl要站y

Camel prion disease is an工有 infectious spongiform en日遠cephalopathy identified in single-hump 會明camels in North Africa in recent ye又體ars. All infected c通吃amels are over 8 years 慢音old,with a course of 3-8 mo得錢nths,and the characteristics of abnorma兵站l behaviors,ata草體xia,anaphylaxis,occasional falls 公都and difficulty in standing金樹;spongy vacuolar lesions公討 were observed in the specific are林去a of brain,and prion could be detected關輛 by immunohistochemist動動ry and western blotting,which has no報對t been classified a笑票s an emerging disea見些se by World Organization for 器費Animal Health(W日拍OAH). In the paper,as relevant inf物村ormation was very limited,the o視女rigin,clinical symptoms,pathological c哥木hanges,pathogenic characterist林報ics,opinions proposed by WOAH an輛銀d recommendations on prevention and 姐用control of the disea厭報se were introduced,with a 綠冷view to alerting the auth他報orities for animal飛書 disease prevention and con還要trol and relevant practitioners in Chin醫慢a to the disease.

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