2019年以來，我國(guó)台灣地區多次暴發(fā)H5亞型禽流感疫情，輛自病原包括H5N2、H5N5、H7N7等亞型禽流感病毒。爲了解台票文灣地區流行的H5亞型禽流感病毒的北玩分子流行特點，下載GenBank Influenz得腦a Virus Database和G影短ISAID中公布的台灣地區所有H5亞型禽流感病毒HA序列，對(duì費雪)近年來公開(kāi)報道(dào)船我的台灣地區流行的H5亞型禽流感病毒進(jìn)行遺傳進(jìn)化分析樹城，并與大陸地區流行的H5亞型禽流感病毒進(jìn)行比較。結我房果顯示：台灣地區同時(shí)存在歐亞譜友書系和美洲譜系兩(liǎng)個分支的H5亞型禽流感病毒流行，而大陸地區放關流行的H5亞型病毒都(dōu)是歐亞譜系。歐亞譜系中，台灣地區流行的主要是第2美湖.3.4.4a分支病毒，而大陸地區流行的主要是2.3.4.4d分支病計船毒，兩(liǎng)個地區流行的H5病毒譜系并不完全一緻。由于台灣地區的雨司禽流感生态系統與大陸地區南方相似，因此台灣地區流行的美洲譜系H5亞型禽流感病購劇毒有通過(guò)野鳥傳播傳入大陸地光亮區的潛在風險，應提高警惕，加強司少禽流感調查監測，嚴厲查處非法走私禽類及其産品的活動。本研究在資爲我國(guó)H5亞型禽流感防控提供了信息支持。。

Phylogenetic Analysi在紙s on H5 Subtype Avi錢費an Influenza Virus in Taiwan of Chin窗藍a

H5 subtype avian influenza（AI）in業了cluding H5N2，H5N5暗議 and H7N7 had taken 微對place several times in Taiwan of China東亮 since 2019. In order 農腦to identify the molec線高ular characteristics of H5 subtype AIV 微喝prevalent in Taiwan，all HA sequen商拍ces of the viruses isolated會舊 from Taiwan registered in GenBan朋鐵k Influenza Virus Resource鐘行 and GISAID Database were dow錢開nloaded to analyze their evolutionary r大說elationships，and thes書飛e H5 subtype AIV st件下rains were compared with those 關樂prevalent in mainland China. The學藍 results showed 兵樹that the H5 subtype AIV北海 prevalent in Taiw開討an belonged to Eurasian or 那飛American lineage，while the s腦多trains prevalent in main好鐘land China only fell into Eurasian l鐵他ineage. For Eurasian linea畫村ge，clade 2.3.4.4a virus was mainly pre林紅valent in Taiwan，whi對窗le clade 2.3.4.4子通d virus was prevalent in mainlan身照d China. As avian influenza ecosyst務女em in Taiwan was similar to that in 讀聽southern mainla關都nd China，the vi靜謝ruses of American lineag外子e prevalent in Taiwan had a p懂地otential risk of being藍為 introduced into mainland山區 China via wild大歌 birds，so it was necessa頻內ry to improve early warning 東又system，strengthen investigation an路秒d surveillance on AIV，investi吧朋gate and handle拍城 with any illega窗答l smuggling of poultry and r對亮elated products. In conclusion，some d男學ata was provided to prev森個ent and control H5 subtype AI in Ch區短ina..

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