新型冠狀病毒研究進(jìn)展

2020-07-17 15:52:08 徐 鵬,劉小花,張昕薇,等 中國(guó)動物檢疫

自2019年12月新型冠狀病毒肺見相炎(coronavirus disease 劇歌2019,COVID-19)暴發(fā)以來,世界各國(guó)相繼科時出現了大量新型冠狀病毒(severe acu件音te respiratory syndrome corona器熱virus 2,SARS-CoV-2)小新感染病例。SARS-CoV-2對(duì)全球公共海購衛生安全造成(chéng)了巨大威脅。疫情發(的開fā)生以來,相關科研人員從SARS-CoV-2的病原學(x去業ué)特點、流行病學(xué)特征、病原學(xué)檢測、科明治療與愈後(hòu)症狀等方面(miàn)進(jìn)行了研究。本文對(d鄉數uì)上述幾個方面(miàn)的研究成(chéng)果進(的廠jìn)行了彙總。研究發(fā)現:SARS-Co制有V-2以其遺傳多樣(yàng)性和重組頻繁的特點不斷産生變異體,以山動更大的傳播力感染人群;目前已知的2種(zhǒn通輛g)傳染途徑爲跨物種(zhǒng)傳播和空金人際傳播,其中飛沫傳播和接觸傳播是人際傳播制還的主要傳播途徑;感染人群遍布各個煙裡年齡段,其中患有慢性疾病的老年人更容易發(fā紅哥)展成(chéng)危重病人;臨床檢測時(shí)聯合核酸件線和抗原抗體檢測,將(jiāng)有助于提高SARS-CoV-2些愛感染的檢出率并排除其他冠狀病毒感染的可能(néng)性;目前尚未有治療C森農OVID-19的特效藥物,臨床上廣泛使用廣譜抗病毒藥物或中藥來治療各知林種(zhǒng)症狀;全球各國(guó)正在加緊研發湖訊(fā)SARS-CoV-2疫苗話市,部分疫苗已進(jìn)入臨床試驗階段。本文有助于全面(miàn)了解SA坐來RS-CoV-2的研究狀況,也爲熱分其後(hòu)續研究及防治提供了參考。

Research Progress on S冷好ARS-CoV-2

A large number o還問f cases infected w雪東ith severe acute respira到在tory syndrome corona動腦virus 2(SARS-CoV-2)have appeared in m又熱any countries since December員費 2019 when the outbrea老北k of coronavirus disease 2現如019(COVID-19)occurred,which has 些秒posed huge threat to 如厭global public health. SARS-CoV-2 has去用 been studied by relevant re日制searchers based on its etiology,ep森體idemiological characteristics,etiolo歌新gy detection,therapy and progn煙長osis since the outbreak,and 湖不the research re我如sults were summarized in th微厭is paper as follows:variants had bee藍嗎n produced by SARS-CoV-2 due to its 票北genetic diversity and f銀男requent recombination,which had infect水器ed an increasing number 樹會of people with stronger 國會transmission;two pathways i女風ncluding cross-species and interpe房照rsonal transmission had笑能 been known at present,in wh問厭ich,the main pathways of interper生煙sonal transmission included droplet an見分d contact transmission;peop廠草le at all ages might be們見 infected,especially the elderly話兒 with chronic diseases were mo厭上re likely to become c劇男ritical patients;the detection r爸分ate might be improved b雜公y the combination of detec明我tion of nucleic acid and an哥電tigen antibody that cou行廠ld eliminate the poss人件ibility of other coronavirus infectio弟分n;no effective drugs for COVID-19些城 had been availabl有銀e at present,instead話制,broad-spectrum a聽開ntiviral drugs or traditional C紙身hinese medicine were wi空了dely used in cl資朋inical practice;the development 放紅of vaccines against SARS-CoV-2 had 視美been sped up by all countries,and so事喝me vaccines had been at clinical 身還trial stage. The status of devel兵風opment of SARS-CoV-2 were summarized線報 in this paper,which also provi我服ded some references 去民for future study and 家議control of it.

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